Through a multidisciplinary approach, this textbook connects clinical applications and biological considerations of heterogeneous radiation to a thorough discussion of the physics of heterogeneous radiation. Comprehensive reviews of the fundamental concepts, procedures, dosimetric characteristics, planning techniques, documentation standards, reporting metrics, and clinical practice guidelines are provided for spatially fractionated radiation therapy (SFRT). Presenting the current situation and the findings of clinical patient studies that have the potential to improve the treatment of large and advanced cancers. The present radiobiological understanding of radiation response and radiation therapy design parameters is examined along with any potential biology foundations that might pose a problem. As the subject of heterogeneous radiation quickly develops in terms of technological advancement and clinical inquiry, such comprehensive understanding is an essential foundation.
Key Features:
GRID collimator- and MLC-based GRID therapy
3D Lattice radiation therapy
Flash radiation therapy
Minibeam and microbeam therapy
Proton beam GRID therapy
GRID and Lattice therapy plan evaluation and documentation
Clinical applications of SFRT and patient outcomes
Monte Carlo simulation techniques of SFRT
Practical applications and procedures (where appropriate)
Biological correlations and potential biological underpinnings
Immune phenomena in SFRT
