Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing.
New to this edition:
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- Expanded and updated content in every chapter, with new material on:
- • non-inferiority trials for comparative effectiveness research
- • incidence-density case-control studies
- • confounding and effect modification
- • diagnostic test studies to inform prediction rules
- • ethical aspects of whole genome sequencing
- • automated data management approaches
- • new NIH grant-writing requirements
Color format, and
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